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PRODID:icalendar-ruby
CALSCALE:GREGORIAN
BEGIN:VEVENT
DTSTAMP:20260830T203605Z
UID:8ba1c300-be79-4143-96d1-c4e003236ba3
DTSTART:20251113T090000Z
DTEND:20251113T170000Z
DESCRIPTION:Small molecules (or chemicals) play a crucial role in biologica
 l systems\, acting as precursors to macromolecules\, cells\, and tissues. 
 Beyond this\, they are involved in cell signalling\, regulation\, energy 
 consumption and production\, and can be used therapeutically to treat dise
 ases. Metabolites\, a subset of small molecules\, are the chemical interme
 diates and/or end products of metabolic processes.\n\nTo understand the ro
 le of chemicals in a biological context\, we can study how they bind to an
 d impact the function of their macromolecular targets\, such as DNA\, RNA\
 , and protein. We can also assess their broader functional impact on cells
 \, tissues\, blood\, and other biofluids.\n\nThis six-hour virtual worksho
 p offers hands-on experience with EMBL-EBI tools and resources to explore 
 the biological effects of small molecules. Using a case study\, we will gu
 ide participants through workflows to investigate drug interactions with a
  protein target\, as well as assess the downstream effects within a biolog
 ical system. \n\nWe will use [ChEMBL](https://www.ebi.ac.uk/chembl/) to 
 identify small molecule drugs and experimental data on their impact on tar
 gets\, [PDBe](https://www.ebi.ac.uk/pdbe/) to evaluate target binding det
 ails\, and [MetaboLights](https://www.ebi.ac.uk/metabolights/) to investi
 gate the small molecule’s impact on biological systems.  \n  \n  \n**Vir
 tual course**\n\nThis course will take place on Zoom. Trainers will be ava
 ilable to assist during practical sessions\, answer questions\, and provid
 e further explanations during the Zoom.\n\nTo join the course you will nee
 d to create an [EMBL-EBI Training website account](https://www.ebi.ac.uk/t
 raining/user/login).  \n 
SUMMARY:Chemicals in a biological context: metabolites\, drugs\, and beyond
URL;VALUE=URI:https://www.ebi.ac.uk/training/events/chemicals-biological-co
 ntext-metabolites-drugs-and-beyond
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